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Deoxycorticosterone acetate
CAS No. 56-47-3
Deoxycorticosterone acetate ( Deoxycorticosterone Acetate | DOCA | Percotol | Cortexone acetate | )
产品货号. M15055 CAS No. 56-47-3
醋酸脱氧皮质酮是一种类固醇激素,用于肌内注射,用于肾上腺皮质类固醇的替代治疗。
纯度: >98% (HPLC)
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规格 | 价格/人民币 | 库存 | 数量 |
50MG | ¥292 | 有现货 |
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100MG | ¥373 | 有现货 |
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200MG | ¥551 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Deoxycorticosterone acetate
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述醋酸脱氧皮质酮是一种类固醇激素,用于肌内注射,用于肾上腺皮质类固醇的替代治疗。
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产品描述Deoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.
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体外实验——
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体内实验Animal Model:MR (mineralocorticoid receptor) mutant mice (MRCdh5Cre)?and MR wild-type mice (MRwild-type) treated with unilateral nephrectomy (12-week-old) Dosage:2.5 mg/d Administration:Subcutaneous implantation; 42 days; treated with 2 mg Tamoxifen (HY-13757A) (20?mg/mL in sunflower oil and 10% ethanol; i.p.; once daily on?5 consecutive days) at least 4 weeks before nephrectomy Result:Increased the blood pressure without differences between both genotypes (MRCdh5Cre and MRwild-type).Resulted glomerular injury and proteinuria, renal inflammation and fibrosis.
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同义词Deoxycorticosterone Acetate | DOCA | Percotol | Cortexone acetate |
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通路Others
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靶点Other Targets
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受体Others
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研究领域Endocrinology
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适应症——
化学信息
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CAS Number56-47-3
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分子量372.5
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分子式C23H32O4
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纯度>98% (HPLC)
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溶解度Ethanol: 6 mg/mL (16.1 mM); DMSO: 11 mg/mL (29.53 mM)
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SMILESCC(OCC([C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O)=O
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化学全称[2-[(8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Schenk J, et al. J Pharmacol Toxicol Methods, 1992, 27(3), 161-70.
产品手册
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