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Deoxycorticosterone acetate

CAS No. 56-47-3

Deoxycorticosterone acetate ( Deoxycorticosterone Acetate | DOCA | Percotol | Cortexone acetate | )

产品货号. M15055 CAS No. 56-47-3

醋酸脱氧皮质酮是一种类固醇激素,用于肌内注射,用于肾上腺皮质类固醇的替代治疗。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
50MG ¥292 有现货
100MG ¥373 有现货
200MG ¥551 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Deoxycorticosterone acetate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    醋酸脱氧皮质酮是一种类固醇激素,用于肌内注射,用于肾上腺皮质类固醇的替代治疗。
  • 产品描述
    Deoxycorticosterone acetate is a steroid hormone used for intramuscular injection for replacement therapy of the adrenocortical steroid.
  • 体外实验
    ——
  • 体内实验
    Animal Model:MR (mineralocorticoid receptor) mutant mice (MRCdh5Cre)?and MR wild-type mice (MRwild-type) treated with unilateral nephrectomy (12-week-old) Dosage:2.5 mg/d Administration:Subcutaneous implantation; 42 days; treated with 2 mg Tamoxifen (HY-13757A) (20?mg/mL in sunflower oil and 10% ethanol; i.p.; once daily on?5 consecutive days) at least 4 weeks before nephrectomy Result:Increased the blood pressure without differences between both genotypes (MRCdh5Cre and MRwild-type).Resulted glomerular injury and proteinuria, renal inflammation and fibrosis.
  • 同义词
    Deoxycorticosterone Acetate | DOCA | Percotol | Cortexone acetate |
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Endocrinology
  • 适应症
    ——

化学信息

  • CAS Number
    56-47-3
  • 分子量
    372.5
  • 分子式
    C23H32O4
  • 纯度
    >98% (HPLC)
  • 溶解度
    Ethanol: 6 mg/mL (16.1 mM); DMSO: 11 mg/mL (29.53 mM)
  • SMILES
    CC(OCC([C@H]1CC[C@@]2([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=O)=O
  • 化学全称
    [2-[(8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Schenk J, et al. J Pharmacol Toxicol Methods, 1992, 27(3), 161-70.
产品手册
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